Breaking the Silence: Ending the Cycle of Intergenerational Addiction

We have all heard stories from our parents about becoming addicted to drugs or about that one uncle who abuses substances. When we talk about addiction, we often focus on an individual's choices, bad behavior, or immediate environment. However, for many, the roots of substance issues trace back before they were even born. It comes from decades of family history, past abuses, and generational trauma.

First, according to the Substance Abuse and Mental Health Services Administration (SAMHSA), they “consider dependence on alcohol or drugs to be a long-term illness, like asthma, hypertension (high blood pressure), or diabetes” [1]. They also say that not only do genetics play a part in the chance of developing a substance abuse disorder, but also someone's environment, psychological traits, and stress level [1]. A substance abuse disorder is a serious classification of disease that should be met with compassion, understanding and a comprehensive strategy rather than judgement or isolation.

Next, to understand the causes of substance abuse we must analyze the link between a difficult childhood and a negative adulthood. According to the CDC’s landmark Adverse Childhood Experiences (ACE) study, they found that adverse childhood experiences can have “long-term negative impacts on health, opportunity and well-being” including toxic stress and “unstable work histories as adults and struggle with finances, job stability, and depression throughout life” [2]. Many of these negative consequences can lead to a turn to a dependence on substances.

Other research shows a direct relationship between generations, that the “empirical evidence is clear that parent substance use predicts substance use among offspring” [3]. Also that “intergenerational continuity in substance use appeared to be largely due to the transmission of a general tendency to use substances, rather than substance-specific mechanisms” [3]. In summary, if your parents abused drugs, you are more likely to as well, along with your kids. This cycle usually repeats generation after generation.

Another unaddressed aspect of this substance abuse issue is the concept of stigma. In many families, a family member’s substance abuse is hidden. This secrecy inadvertently teaches the next generation similar behaviors if they go on to develop a substance abuse disorder. It was found that “perceived stigma in substance abuse was linked to poorer mental health” and was “associated with lower self-esteem, higher depression and anxiety, and poorer sleep [4]. On the other hand “perceived social support was linked to greater mental health” [4]. Overall, this stigmatization can unintentionally deprive individuals of the social support necessary to recover and reinforce harmful behavior.

Combatting this concept of intergenerational substance abuse is complicated but many people are working on different solutions. First the CDC is “committed to building systems and communities that nurture development” and to “prevent ACEs before they happen, and buffer the risk of harm when they do happen” [2]. Secondly, getting abusers to use social support can also mitigate the negative impact of internalized stigma and health [4]. Finally ,“successful preventive interventions in substance abusers “may not only reduce conduct problems and substance use” but “may also affect positive development in the next generation” [3]. Ultimately, these intergenerational issues can be addressed through the right support.

In conclusion, generational trauma and abuse may be built on someone past, but can be combatted in the present to prevent its spread into the future generations. By understanding the science of addiction and destigmatizing substance abuse, we can dismantle the barriers to recovery and help the next generation.

Reviewed By: Vedant Patel

References

[1] Substance Abuse and Mental Health Services Administration. (2014). What is Substance Abuse Treatment? A Booklet for Families. U.S. Department of Health and Human Services. https://library.samhsa.gov/sites/default/files/sma14-4126.pdf.

[2] Centers for Disease Control and Prevention. (2024). About Adverse Childhood Experiences. U.S. Department of Health and Human Services. https://www.cdc.gov/aces/about/index.html.

[3] Bailey, J.A., Hill, K.G., Oesterle, S. et al. (2006).  Linking Substance Use and Problem Behavior Across Three Generations. Journal of Abnormal Child Psychology.  https://doi.org/10.1007/s10802-006-9033-z. 

[4] Birtel, M.A., Wood, L., Kempa, N.J. (2017). Stigma and Social Support in Substance Abuse: Implications for Mental Health and Well-being. Psychiatry Research. https://doi.org/10.1016/j.psychres.2017.01.097. 

Does AA Actually Work?

In a 2014 survey by the National Survey on Drug Use and Health, about 27.9 million people in the United States had Alcohol Use Disorder (AUD) [1]. AUD is defined as an addictive disorder where people depend on alcohol for everyday functioning, despite negative consequences that affect their physical and mental wellbeing [2]. According to the DSM-5, some of the diagnostic criteria for AUD include “recurrent alcohol use resulting in a failure to fulfill rote obligations”, “recurrent alcohol use in situations in which it is physically hazardous”, and “a great deal of time is spent in activities necessary to obtain alcohol, use alcohol, or recover from its effects” [3]. In addition to its burden on mental health and hindrance of life obligations, AUD can cause a variety of chronic health complications such as alcohol-induced cardiomyopathy, cirrhosis of the liver, and delirium tremens [2]. 

Alcoholics Anonymous (AA) has become one of the most popular forms of treatment for patients with AUD. AA serves as a low-cost way for people suffering from AUD to get support in their recovery. AA programs can be found all across the United States and have no membership requirements other than someone who wants to get help for their unhealthy relationship with alcohol. AA runs on a “twelve steps and twelve traditions” process where people in the program will work through steps built on honesty, courage, and humility. This functions to build a community for individuals with AUD in recovery through sponsorship programs with others who had previously suffered with AUD and share wisdom from their road to recovery [4].

Despite its ability to foster this community, is AA actually effective in initiating and sustaining cessation of alcohol use? Although it is often difficult to get accurate data about the efficacy of AA because of the program’s anonymity policy, there have been a multitude of studies completed to attempt to understand how well AA works. Throughout many studies, a positive correlation has been found between continued abstinence and attendance of AA. Additionally, there has been a lot of support for the increase in people staying sober and the number of AA meetings that they consistently attend [5]. While retention rates remain low at nearly 40%, the AA reported that only about 27% of consistent members stayed sober for less than a year, with over 22% being sober for more than 20 years [6]. However, the efficacy of each individual step within AA has been contested, indicating that the effectiveness of AA does not lay in the actual groundwork of the program, but instead from the stability and community the program builds for participants [5]. For many AA participants, being able to develop a sense of identity with people who have similar struggles in AA helps them stay sober [7].

In a 2020 review study by Stanford spanning over 10,000 participants, AA was found to be at least equally effective as psychotherapy in helping patients achieve sobriety [8]. The professor who ran the study at Stanford, Dr. Keith Humphreys, attributes the success of AA to the social interaction that it emphasizes, with many participants highlighting the importance of the sponsorship program [4, 8]. This is promising for patients struggling with AUD because of AA’s easy access, especially in comparison to psychotherapy which includes cost and access barriers. For instance, “X” study showed that treatment costs were reduced by approximately $10,000 per person when choosing AA over traditional therapy [8]. 

While  AA may not work for everyone, it is clear that, for many people, it has become the right program they need to get and stay sober from alcohol. AA’s effectiveness appears to lay within the community building the program allows and the low barrier to entry. With this in mind, other programs focused on helping people with different forms of addiction could help improve their effectiveness by attempting to imitate AA’s emphasis on interconnectivity and availability. 

Reviewed By: Clare Williams

Designed By: Devin Mulcrone

References

[1] National Institute on Alcohol Abuse and Alcoholism. (2025). Prevalence of Past-Year Alcohol Use Disorder (AUD) https://www.niaaa.nih.gov/alcohols-effects-health/alcohol-topics/alcohol-facts-and-statistics/alcohol-use-disorder-aud-united-states-age-groups-and-demographic-characteristics

[2] Cleveland Clinic. (2025). Alcohol Use Disorder https://my.clevelandclinic.org/health/diseases/3909-alcoholism

[3] RAND Corporation. (2021). Diagnostic Criteria Checklist https://www.rand.org/content/dam/rand/pubs/tools/TLA900/TLA928-1/resources/step-2/AUD/RAND_TLA928-1.diagnostic-checklist_AUD.pdf

[4] Alcoholics Anonymous. (2026). What is A.A.? https://www.aa.org/what-is-aa

[5] Kaskutas, Lee Ann. (2009). Alcoholics Anonymous Effectiveness: Faith Meets Science. Journal of Addictive Diseases Vol 28, Issue 2. Doi: 10.1080/10550880902772464

[6] Wagener, Dan. (2025), Alcoholics Anonymous: The 12 Steps of AA & Success Rates American Addiction Centers https://americanaddictioncenters.org/rehab-guide/12-step/whats-the-success-rate-of-aa

[7] Bulumac, Adriana Lavinia. (2024). Affiliation to the Alcoholics Anonymous (AA) community: A qualitative study on differences between highly affiliated and low/non-affiliated individuals. Nordic Studies on Alcohol and Drugs. Vol 41, Issue 6. Doi: 10.1177/14550725241278089

[8] Erickson, Mandy. (2020). Alcoholics Anonymous most effective path to alcohol abstinence. Stanford Medicine Psychiatry & Mental Health https://med.stanford.edu/news/all-news/2020/03/alcoholics-anonymous-most-effective-path-to-alcohol-abstinence.html

Afrin Addiction: When Breathing Easy Becomes a Compulsion

Afrin is unassuming: it’s an over the counter decongestant nasal spray that doesn’t require an ID to purchase. There are no viral news stories of people cooking up street drugs with it (unlike certain cough medicines) and it does not require a prescription to purchase. However, hiding behind its subtle packaging lurks one of the most habit-forming medications on the market. Afrin uses the active ingredient oxymetazoline to constrict the blood vessels in the nose to allow air to pass more easily through the nostrils and is intended for short-term use, as in before a flight or during a brief illness [1]. When someone uses Afrin for more than 2-3 days in a row or uses it many times per day, the structures in the nose whose job it is to filter and warm up the air we breathe become blocked by the medication, leading to chronic sinus infections and worsened breathing [1]. In addition, constant constriction of the blood vessels with Afrin use can cause them to swell more easily in the absence of Afrin, leading to inflammation and the feeling of a “stuffy nose” whenever Afrin is stopped [2]. This makes it nearly impossible for the person dependent on Afrin to experience the same level of decongestion without Afrin and creates a negative feedback loop where the “solution” to the congestion appears to be more Afrin, which temporarily relieves the symptoms but has diminished results over time.

What makes this addiction so dangerous is that it isn’t as obvious as dependence on opioids or cigarettes, but can still have lasting health consequences. For example, long-term use can cause permanent damage to the nasal mucosa which can lead to frequent nosebleeds and more frequent viral infections due to the chronic dryness and lack of filtration from the medication [3]. The solution to this hidden addiction is awareness. Someone who is advised by a physician or other provider to use Afrin for a short-term illness may assume that no harm could come from using it for more time than prescribed. Already, some ENT providers are warning their patients about how “habit forming certain over the counter nasal sprays can be” and are emphasizing the importance of sticking to the prescribed dosage and timing [4]. The Afrin addiction crisis is stealthy and often flies under the radar, but improved communication and education about the dangers of certain nasal sprays can help people breathe easier in the long term.

Reviewed By: Benji Forman References

[1] “Breaking the Habit: Understanding Afrin Addiction.” Sinus and Allergy Wellness Center of North Scottsdale. https://www.sinusandallergywellnesscenter.com/breaking-the-habit-understanding-afrin-addiction/

[2] Larsen, D. “Can you get addicted to certain nasal sprays?” Southwest Ohio ENT Specialists. https://soents.com/can-you-get-addicted-to-certain-nasal-sprays/

[3] Elangovan, S (2024). “The Hidden Risks of Chronic Nasal Decongestant Use.” Resolve ENT. https://www.resolveent.com/blog/1215240-the-hidden-risks-of-chronic-nasal-decongestant-use/

[4] Correspondence with Dr. Michael Gaslin, ENT